VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Cat

Scientific Name: Felis catus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Carnivora-> Feliformia-> Felidae

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Small ruminant morbillivirus

Family: Paramyxoviridae

Receptor: NECTIN4

Receptor NECTIN4 information

Summary: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0028 2021.04 10X Genomics Esophagus Normal 1928 Link
Vthunter_0029 2021.04 10X Genomics Eyelid Normal 679 Link
Vthunter_0030 2021.04 10X Genomics Heart Normal 8209 Link
Vthunter_0031 2021.04 10X Genomics Kidney Normal 2831 Link
Vthunter_0032 2021.04 10X Genomics Liver Normal 7889 Link
Vthunter_0033 2021.04 10X Genomics Lung Normal 8591 Link
Vthunter_0034 2021.04 10X Genomics Rectum Normal 1503 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of NECTIN4 in human tissues   [NCBI]

Expression: Biased expression in skin (RPKM 30.6), esophagus (RPKM 23.7) and 7 other tissues

Protein expression of NECTIN4 in human tissues   [Proteinatlas]